Maternal gestational diabetes mellitus associates with altered gut ...
WEBJul 1, 2024 · Utilizing large-scale longitudinal fecal samples from 264 mother-baby dyads, we present the gut microbiome trajectory of the mothers throughout pregnancy and infants during the first year of life. GDM mothers had a distinct microbiome diversity and composition during the gestation period.
Interactions between host and gut microbiota in gestational …
WEBMay 10, 2024 · In this review, we summarized gut microbiota signature in GDM pregnancies of each trimester, and presented a brief introduction of microbiome derived SCFAs. We then discussed mechanisms of microbiome-host interactions in the physiopathology of GDM and associated metabolic disorders.
Clinical significance of the genetically variable landscape of the gut ...
WEB6 days ago · The composition of the gut microbiome has been recorted to be strongly associated with gestational diabetes mellitus (GDM), but mutational characterization of the microbiome in patients with GDM has been overlooked. Here, we revealed the genetic variation landscape of the gut microbiome and assessed its clinical significance in a cohort of patients with GDM.
Gut Microbiota and Gestational Diabetes Mellitus: A Review of Host-Gut ...
WEBMay 15, 2020 · In this review, we addressed gut microbiota dysbiosis and the possible mechanistic links between the host and gut microbiota in women with GDM. Furthermore, this review highlights the potential therapeutic use of probiotics in post-GDM women as a T2DM preventive strategy.
Gestational diabetes is driven by microbiota-induced inflammation ... - Gut
WEBFurthermore, the gut microbiome appears to play a role in inflammation-induced GDM pathogenesis, with interleukin-6 as a potential contributor to pathogenesis. Potential GDM markers, including microbiota, can serve as targets for early diagnostics and therapeutic intervention leading to prevention.
Gut Microbiota and Gestational Diabetes Mellitus: A Review of Host-Gut ...
WEBMay 14, 2020 · Accumulating evidence strongly associates gut microbiota dysbiosis in women with GDM, similar to the T2DM profile. Several metagenomics studies have shown gut microbiota, such as Ruminococcaceae, Parabacteroides distasonis, and Prevotella, were enriched in women with GDM.
Gut microbiota and gestational Diabetes Mellitus: A systematic …
WEBGut microbiota could be a biomarker for early detection of GDM and could be considered a potential target for modification to reduce the risk of GDM. This systematic review showed that there is a relationship between intestinal microbiota and GDM.
Alterations of gut microbiota in gestational diabetes patients during ...
WEBAug 26, 2021 · This study aims to reveal the different gut compositions between GDM and normoglycemic pregnant women and find the relationship between gut microbiota and GDM. Fecal microbiota profiles from women with GDM (n = 21) and normoglycemic women (n = 32) were assessed by 16S rRNA gene sequencing.
Diet-Gut Microbiota Interactions and Gestational Diabetes Mellitus (GDM)
WEBFeb 3, 2019 · An impaired gut microbiota has been found in pregnancies complicated by GDM. The microbiota of GDM patients can be transmitted to the offspring. Early modulation of the gut microbiota might be warranted in women at risk of developing GDM.
Mommy’s microbes: Gestational diabetes mellitus shapes ... - Cell …
WEBJul 10, 2024 · Gestational diabetes mellitus (GDM) is associated with increased risk of metabolic and neurodevelopmental disorders in offspring. In this issue of Cell Host & Microbe, Wang et al. provide evidence that changes in the gut microbiome of mothers with GDM may lead to dysbiosis in their infants and altered development in a …