Progressive neurological diseases slowly rob patients of physical abilities and hope. Treatments are urgently needed, but traditional small molecule drug discovery is often difficult. An alternative ...

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Across the studies of a new analysis, there was a significant risk difference in motor milestone response and improvement in Hammersmith Infant Neurological Examination score. Although more ...

According to the researchers, the findings are paving the way toward precision medicine and may have broader use in tracking treatment response in adult-onset motor neuropathy in the future. A recent ...

Nusinersen is an antisense oligonucleotide drug that modulates pre–messenger RNA splicing of the survival motor neuron 2 (SMN2) gene. It has been developed for the treatment of spinal muscular atrophy ...

Nusinersen injection is injected intrathecally (into the backbone) over 1-3 minutes so that it reaches the cerebrospinal fluid (CSF), the fluid that bathes the brain and the spinal cord. Dosage & When ...

Please provide your email address to receive an email when new articles are posted on . Treatment with nusinersen led to continued and improved motor function up to 5 years after initial dose in ...

The appraisal committee (section 5) considered evidence submitted by Biogen Idec and a review of this submission by the evidence review group (ERG). See the committee papers for full details of the ...

A preliminary investigation by the Chongqing Municipal Health Commission has found that a doctor at the Chongqing Medical ...

Ionis Pharmaceutical (NASDAQ: IONS) shares jumped 30 percent on Monday on positive news of phase 3 data for its spinal muscular atrophy drug called Nusinersen, on which it partnered with Biogen ...

Next review: The guidance on this technology will be reviewed and published by the end of the managed access agreement in 5 years. There is a managed access agreement, which includes a commercial ...