Researchers from the Icahn School of Medicine at Mount Sinai have discovered a molecular switch in neurons that limits the ...

Can we regrow damaged nerves? A new study identifies the AHR protein as the switch that limits axon regeneration.

A research team led by investigators at McMaster University has identified an axonal guidance signaling pathway that cancer cells use to infiltrate the brain. The combined results of preclinical in ...

RNA granules, sites for the storage, transport, and regulation of RNA molecules within cells, are transported along axons and then translated locally, far from the cell body. Recent studies suggest ...

Axonal degeneration and neuroinflammation are increasingly recognised as pivotal processes in the pathogenesis of neurodegenerative diseases. Axonal degeneration refers to the progressive ...

Disarm Therapeutics, a biotechnology company creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central driver of neurological disease, today announced ...

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Absolutely. The electrophysiologic characteristics of neuronopathies and axonopathies depend on how long the condition has been present. In the acute states, there is moderate-to-severe denervation, ...

Axonal regeneration in the adult central nervous system is extremely limited after injury. As a consequence, there is typically little functional recovery after spinal cord injury, traumatic brain ...

Axonal damage causes neurological defects in multiple sclerosis. In vivo imaging in mouse models of multiple sclerosis now shows a reversible and sequential process of focal axonal degeneration (FAD) ...

Alzheimer's dementia is caused by accumulation of amyloid-β protein in neurons, formed from proteolytisis of amyloid precursor protein (APP), but the normal role of APP in the brain remains unclear.