BK channels (large-conductance, Ca2+-dependent K+ channels) are essential for the regulation of important biological processes such as smooth muscle tone and neuronal excitability. New research shows ...
In 2004, Washington University in St. Lous researcher Jianmin Cui was handed a puzzling clue to the structure of an ion channel his lab had been studying for five years. Scientists at the Cleveland ...
Potassium channels are critical structures in biology; they selectively allow potassium ions to pass through the membrane surrounding cells. The precise gating of that channel is essential to its ...
SPG601 is an investigational small molecule large-conductance, calcium-activated potassium channel activator. The Food and Drug Administration (FDA) has granted Fast Track designation to SPG601 for ...
LONDON, July 25, 2024 (GLOBE NEWSWIRE) -- Kaerus Bioscience Ltd. (www.kaerusbio.com), a clinical-stage biotechnology company focused on developing therapeutics for rare genetic syndromes of ...
Researchers have discovered a new mechanism for potassium channel inhibitor entry, which could improve the specificity of drugs targeting the channel. Upon binding to calcium ions, BK channels allow ...
Scientists have discovered that an ion-channel mutation that causes epilepsy may do so by making part of the channel protein stiffer, so that the channel toggles open more easily. This is the first ...
LONDON, March 11, 2025 (GLOBE NEWSWIRE) -- Kaerus Bioscience (www.kaerusbio.com), a clinical-stage biopharmaceutical company created by Medixci for the development of therapeutics for rare genetic ...
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