Sinclair et al. combine quantitative proteomics and an autophagy flux reporter to map autophagy substrates and triggers during CD8 T cell differentiation. Proteins degraded and fueled by ...

Our immune system is constantly working to protect us from infections and injuries. One of its most powerful tools is ...

Hepatocellular carcinoma (HCC), the third leading cause of cancer-related deaths worldwide, remains one of the most ...

CD8 T cells transform ... The research team found that a protein called Kruppel-like factor 2 (KLF2) was the only one they ...

CD8 + T cells accumulate in atherosclerotic plaques ... cells of these vessels express large amounts of the signaling protein CXCL12. "These findings furnish new lines of approach for therapeutic ...

Mutations in tumor cells can create neoantigens, novel proteins not present in normal ... patients developed strong neoantigen-specific CD8 + T cell responses following vaccination.

and the CD3+ CD4-CD8+ ratio was 21.7% for the negative control group (without IL-2). The outcome demonstrates that the activity of IL-2 Protein (Competitor N) and GMP Human IL-2 Protein ...