Here authors show that NKG7, a lysosomal protein specifically expressed in CD8 + T cells, inhibits mTORC1 function via the lysosomal proton pump, vacuolar ATPase, promoting antitumor activity ...

A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8 + T cell division for the generation of memory precursor cells.

Olga Rivera Ballesteros from the Center for Infectious Medicine (CIM) at the Department of Medicine, Huddinge (MedH) is ...

Researchers from the VIB-KU Leuven Center for Cancer Biology, in collaboration with other scientists, have discovered a way ...

CD8 + T cells accumulate in atherosclerotic plaques. LMU researchers identify a crucial signaling pathway—with therapeutic potential. For a long time, macrophages and foam cells were considered ...

Certain immune cells in MS show abnormalities in activity and signs of reactions against the Epstein-Barr virus, a study says ...

two thirds has not – which implies this unchanged genetic coding is serving an important function. What's more, the researchers found that a specific human T cell – the CD8+ "killer ...

Hepatocellular carcinoma (HCC), the third leading cause of cancer-related deaths worldwide, remains one of the most ...

Proper immune system function is paramount for human survival against infectious ... Once acquired infection persists for life requiring continuous life long cellular immunity (CD8 memory T cell and ...

metabolism and function. A functional single-cell metabolic survey identifies Elovl1 as a target to enhance CD8 + T cell fitness in solid tumours Through a functional CRISPR/Cas9 screening ...