A team has identified a previously unknown phase of the immune response. The results challenge long-standing assumptions about the process called 'T-cell priming'. These new insights have significant ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

A team from the Max Planck Research Group for Systems Immunology at the University of Würzburg has identified a previously ...

The research groups led by Wolfgang Kastenmüller and Georg Gasteiger employed innovative microscopy techniques to observe how ...

It’s like performing a full-body scan of the T cell to examine its phenotype and function. We tested TetTCR-SeqHD using human polyclonal CD8+ T cells with known antigen specificity and TCR ...

When PD-1 binds to PD-L1 or PD-L2 on tumor cells or other cells, T cell functions are subdued ... cells taking up tumor-derived proteins and presenting them to antigen naive CD8+ T cells present in ...

A team from the Max Planck Research Group for Systems Immunology at the University of Würzburg has identified a previously ...