San Francisco 49ers RB Christian McCaffrey rushed and caught for 121 yards, scoring three touchdowns in the team's Week 11 win over the Arizona Cardinals.

Watch the best plays from San Francisco 49ers running back Christian McCaffery's 142-yard game against the Carolina Panthers ...

Atlanta Falcons quarterback Kirk Cousins' 19-yard pass locates wide receiver Deven Thompkins as WR approaches sideline.

Christian McCaffrey plays football like he was built for it because, in many ways, he was. Competitive drive runs in his ...

McCaffrey, one of the best receiving running backs in NFL history, plays his former team on "Monday Night Football." ...

San Francisco 49ers QB Brock Purdy, TE George Kittle, RB Christian McCaffrey, and DL Clelin Ferrell recapped key plays ...

Christian McCaffrey was a steady force as the San Francisco 49ers won a sloppy "Monday Night Football" game against the Carolina Panthers.

Christian McCaffrey remains extremely productive for the San Francisco 49ers in his age-29 season, and in at least one way, ...

These are five of fantasy football's biggest stars with the most difficult playoff schedules as the regular season comes to a ...

SANTA CLARA. Calif. (AP) — Christian McCaffrey has long been the standard when it comes to dual-threat running backs in the NFL with his ability to run routes like a receiver on the outside as well as ...