Using microscopy and biochemical studies, they concluded that SFV was entering cells by using the clathrin-mediated endocytosis pathway. Helenius's work linked the story of viruses to the story of ...

Clathrin-mediated endocytosis is a major endocytic route used by transferrin, growth-factor receptors and pathogenic viruses during infectious entry. Although clathrin-dependent uptake is the best ...

In our lab, we focus on clathrin-mediated endocytosis, the predominant route for membrane internalisation in most cells. In addition to its role in endocytosis, the clathrin machinery also forms ...

Cells use many different mechanisms for endocytosis. In clathrin-mediated endocytosis, cell surface receptors selectively ...

Clathrin-mediated endocytosis (CME) plays a crucial role in synaptic vesicle trafficking, and it has been hypothesized that CME impairment contributes to neuropathology related to schizophrenia.

They discovered that GPR107 facilitates the internalization of angiotensin II receptor type 1 (AT1R) in podocytes through clathrin-mediated endocytosis. In diabetic kidneys, GPR107 loss impairs ...