During clathrin-mediated endocytosis, adaptor proteins bind to the cell membrane and to the protein clathrin, assisting in ...

We conclude that endocytosis of FcαR is clathrin- and dynamin-dependent, but is not regulated by Rab5, and the endocytic motif is not located in the cytoplasmic domain of FcαR.

In clathrin-mediated endocytosis, the cell membrane invaginates to take up metabolites, hormones, and proteins from the cell surface into intracellular vesicles.

Living cells and tissues show a high capacity to absorb various chemical compounds from the surrounding environment.

This article provides an introduction to dynamin and endocytosis and lists the inhibitors that are relevant to research.

Prof. Jenny Russinova (VIB-UGent) goes on to highlight the importance of their findings: "Identification of ES9-17 presents several new opportunities in the quest to understand clathrin-mediated ...

A research paper just published in Science China Life Sciences reports that claudin-11 plays an important role in influenza virus endocytosis by disrupting the interaction between the endocytic ...

Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and conveyed ...

An artist's impression of Clathrin-Mediated Endocytosis (CME) occurring as periodic traveling waves on the membrane. Clathin coated vesicles (blue) bud off from wave peaks. Clathrin waves require ...

Clathrin coated pits (CCPs) are spherical, cage-like structures located on the plasma membrane that are responsible for receptor-mediated endocytosis. CCPs bud off the cell membrane with their ...

While it is clear that PICALM figures in clathrin-dependent endocytosis, how this counteracts ApoE4 remains to be seen. Indeed, exactly how ApoE4 affects endocytosis is unclear, and appears to differ ...