The article, “The EGF/EGFR axis and its downstream signaling pathways regulate the motility and proliferation of cultured oral keratinocytes” was published on 27 May 2023 in FEBS Open Bio ...

The EGF signaling pathway regulates cell growth, proliferation, differentiation, and survival through the activation of EGFR and downstream cascades like RAS/RAF/MEK/ERK and PI3K/AKT.

Furthermore, activation of the EGFR pathway by administrating epidermal growth factor (EGF) to the parental lines TPC-1 and FRO before they acquired resistance induced a decrease in lenvatinib ...

EGFR is a receptor on the surface of cells which is expressed in many normal epithelial tissues, including skin. The EGFR signaling pathway is one of the key pathways that regulate growth ...

Cisplatin is a potent chemotherapeutic agent used to treat various cancers, including cervical cancer. But the continued use of cisplatin can lead to the development of cisplatin resistance and other ...

To investigate the expression of sonic hedgehog (SHH) and epidermal growth factor receptor (EGFR) signal molecules in pancreatic cancer cells, and to assess the inhibitory effects through the ...

Signaling pathways in mammalian cells are assembled and regulated by a finely controlled network of protein–protein and protein–phospholipid interactions, mediated by dedicated signaling ...

We have discovered EGFR-dependent signaling pathways that control the types of membrane protrusions that form during cell adhesion which recapitulates the earliest stages of cell migration. Some of ...

Researchers have taken an important step toward what may become a new approach to restore hearing loss. In a new study, out today in the European Journal of Neuroscience, scientists have been able ...

This research demonstrates a signaling pathway that can be activated by different methods and could represent a new approach to cochlear regeneration and, ultimately, restoration of hearing.

Conclusions: In NCI-H292 cells that possess wild-type Keap1, Nrf2-mediated cell proliferation may be regulated by the EGFR/MAPK signaling pathway. On the other hand, in A549 cells, cell proliferation ...

EGFR is a receptor on the surface of cells which is expressed in many normal epithelial tissues, including skin. The EGFR signaling pathway is one of the key pathways that regulate growth ...