The simple idea that apoptosis is tolerogenic or non-immunogenic and that necrosis is immunogenic is an oversimplification. Thus, apoptosis of tumour cells that is induced by chemotherapy can ...

Phosplatin Therapeutics is harnessing immunogenic cell death (ICD) as an alternative mechanism to existing cancer immunotherapy strategies. PT-112, Phosplatin’s lead ICD inducer, is in phase 2 ...