Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 18 (May 3, 2022), pp. 1-9 (9 pages) Regulation of hepatocyte proliferation and liver morphology is of ...

Mayo Clinic scientists uncovered how excessive drinking triggers fatty liver disease by disrupting the enzyme VCP, which ...

The liver is the only internal organ that can regenerate itself. Remarkably, even if 70 percent of the liver is removed, its tissue can regrow into a full-sized organ within a matter of months. By ...

(A) Distinct phases of APAP-ALF. (B) Integrative multimodal approaches, including single-nucleus RNA sequencing spatial transcriptomics, four-dimensional intravital imaging and lineage tracing in both ...

Fluorescence microscopy image of a mouse liver tissue section marked with different fluorescent reporters. Local hepatocyte groups sharing the same reporter are of clonal origin. “Using spatial ...

p53 is one of the most important proteins in cancer biology. Often referred to as a "guardian of the genome," p53 becomes activated in response to various cellular stressors like DNA damage. Its ...

In a new study published in the Journal of Hepatology, researchers from the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) show that only 15–20% of hepatocytes in newborn mice - dubbed ...

Traditional liver perfusion procedures – used to isolate hepatocytes – are difficult to perform and require extensive training, steady hands and long-standing experience. In this webinar, a new, ...

The liver is the primary filter for everything you ingest. Liver cells, or hepatocytes, support this organ's giant job by releasing dozens of various proteins while collecting, sorting, degrading and ...

Researchers identified microRNA-93 as a genetic driver of fatty liver disease and showed that vitamin B3 can effectively ...