Summary: Insulin detemir is a long-acting, neutral, and soluble insulin analogue with a lower within-subject variability of fasting plasma glucose levels than isophane insulin human (NPH insulin ...
The plant will make three types of insulin, which Civica has pledged to sell for $30 a vial and $55 for a box of five pens.
The introduction of Merilog is particularly notable given that it is the third insulin biosimilar approved in the U.S., following the approval of two long-acting insulin biosimilars in 2021.
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a DB = double-blind, DM = diabetes mellitus, HbA 1c = glycosylated hemoglobin, MC = multicenter, NPH = isophane insulin human, NR = not recorded, OL = open-label, PG = parallel-group, R = randomized.