Previously, we reported our experience treating 14 patients with metastatic melanoma using a fully human antibody to cytotoxic T-lymphocyte antigen-4 (anti–CTLA-4) in conjunction with peptide ...

Pembrolizumab and Ipilimumab as Second-Line Therapy for Advanced Melanoma Immunologists have long searched for tumor-rejection antigens: molecules on tumor cells, but not on normal tissues, that could ...

Antibodies are Y-shaped protective proteins manufactured by B lymphocytes in reaction to invading pathogens. When B lymphocytes encounter foreign antigens expressed by antigen-presenting cells (e.g.

A team of researchers from Moffitt Cancer Center has found new insight into why some lung cancer patients do not benefit from tumor-infiltrating lymphocyte, or TIL therapy. Their findings, published ...

Antigens are detected by lymphocytes. Each lymphocyte has several antibodies which can be thought of as detectors. Each antibody is specific to a particular antigen. Typically, because ...

A team of researchers has found new insight into why some lung cancer patients do not benefit from tumor-infiltrating lymphocyte, or TIL therapy. Their findings may help improve future ways to deliver ...

Scientists from the Moffitt Cancer Center say they now have a better understanding why some lung cancer patients do not benefit from tumor-infiltrating lymphocyte, or TIL therapy. Their findings ...

The innate/general resistance system and the adaptive system are the two main subsystems of the immune system. To generate an efficient immune response, the innate and adaptive systems constantly ...

Single-ascending dose portion of study has successfully completed 2.5 and 7 mg / kg levelsDose dependent immunosuppressive effect against a ...