The Role of Succinate and the Krebs Cycle One key discovery was a bottleneck in the Krebs cycle, specifically in the production of succinate, a molecule crucial for generating ATP—the primary energy ...

Alzheimer's nerve cells manifest a decrease in the connections between nerve cells, called synapses, shown here within the blue circles. Half the synapse is marked with a red fluorescent stain and the ...

Nerve cells in the brain demand an enormous amount of energy to survive and maintain their connections for communicating with other nerve cells. In Alzheimer's disease, the ability to make energy is ...

The brain runs on energy. Every thought, memory, or emotion sparks countless signals between nerve cells. That communication demands a steady, powerful fuel supply. Without it, the system breaks down.

Having considered localization of respiratory functions in mitochondria and in prokaryotic cells, it's time to return to the eukaryotic context and follow a molecule of pyruvate across the inner ...

If you took biochemistry classes, chances are good you remember memorizing the Krebs cycle, a well-known metabolic pathway in which sugars are converted through a series of steps to generate ATP, a ...

This week there was news on Long COVID in two very different directions: emergence of strong data to support mitochondrial dysfunction as the basis for the condition in some people, and learning how ...