Murray injured his foot on a fourth-quarter fumble in Week 5. He was placed on injured reserve in Week 10 and will be eligible to return in Week 14 against the Rams, though it could be as the Cardinals’ backup. Head coach Jonathan Gannon said Monday that the team will not open his 21-day practice window this week.

Chargers quarterback Justin Herbert is dealing with a fracture in the back of his left non-throwing hand, and underwent surgery on Monday to fix it. Herbert suffered the injury on the first drive of the win over the Raiders, but returned in the second quarter with a padded glove over his left hand, and finished the game.

The upsets continued into the early window of games on Sunday, with the most notable being the Panthers forcing three turnovers against NFL MVP front-runner Matthew Stafford and shocking the Rams, 31-28. The Texans also took down the Colts, further clogging up the AFC South standings with five weeks to play.

The Colts (8-4) visit the Jacksonville Jaguars (8-4) in NFL Week 14 action. Here are each team's injury report entering the week. He left Week 13 action with a calf injury. He left Week 13 action with a concussion. He left Week 13 action with a hip injury. He left Week 13 action with a back injury.

As the Browns lost to the San Francisco 49ers 26-8 to fall to 3-9 on the season, the news only got worse after the game as a breakout player among the defense w

Morrison is a big absence in the defensive backfield for Tampa. Irving is expected to return to the fold and be part of a hot-hand rotation along with Rachaad White and Sean Tucker, per coach Todd Bowles, who also said Mayfield is trending toward playing. Nelson and Reddick are important pieces of the defensive front.

Los Angeles Chargers running back Omarion Hampton is "likely" to play Monday Night against the Philadelphia Eagles, according to CBS Sports.

There are more than a dozen high profile players on this week's injury report that may leave fantasy football players scrambling.

Aaron Rodgers is out with a serious looking injury on Sunday. The veteran NFL quarterback was on the receiving end of a massive hit against the Buffalo Bills on Sunday. Rodgers, 41, is currently playing through multiple fractures in his left wrist.

Indianapolis Colts cornerback and former New York Jets star Sauce Gardner suffered a calf injury during the team's 20-16 loss to the Houston Texans on Sunday. While the diagnosis is more positive than initially feared, Gardner is expected to miss several games recovering from the soft-tissue injury.