The cellular waste disposal system called the proteasome is best known for its central role in protein degradation and recycling, but as far back as the 1990s it was shown that products of this ...

One of the key elements of that system is the proteasome, a structure that chops up proteins that are faulty or no longer needed into smaller pieces known as peptides. These fragments might be ...

Reporting in Nature, Lin and colleagues show that selective inhibition of the mycobacterial proteasome with certain oxathiazol-2-one compounds might be useful in targeting this non-replicating ...

Proteasomes are vital in maintaining cellular ... or refraining from, any action on the basis of the content on our site.

Scientists discover new part of the immune system - and it could help solve our antibiotics crisis - Experts say the findings have the potential to transform the treatment of infectious diseases ...

The research focused on a specific part of the cell called the proteasome, which carves old proteins into smaller chunks so they can be recycled to make new ones. Through a series of experiments, ...

The research focused on a specific part of the cell called the proteasome, which breaks down old proteins into smaller pieces to recycle them for new ones. Through various experiments, scientists ...

This review summarizes the mechanisms of action and clinical activity of IMiDs ... immunomodulatory drugs (IMiDs) and the proteasome inhibitor bortezomib. [1] IMiDs are structural and functional ...