This discovery, published in Nature, could greatly improve the fight against antibiotic-resistant superbugs. Structure of a proteasome molecule. The proteasome is present in all cells of the body. Its ...

The company's focus is on creating small-molecule therapeutics that enhance ... chief scientific officer Dr Diogo Feleciano ...

By focusing on increasing levels of cyclic guanosine monophosphate (cGMP)—a signaling molecule involved in ... in protein ...

Molecular glue degraders are small molecules that promote the interaction of a target protein with an E3 ubiquitin ligase to induce proteasome ... The small molecule UM171 was previously ...