Unusually, the degradation of Rpn4 is largely ubiquitin independent, which highlights its function as a dedicated proteasome sensor and, furthermore, rules it out as being the ubiquitin sensor.

A team of scientists has just revealed an unsuspected function of the immune ... light on a hidden ability of the proteasome, an essential cellular structure, to produce antibacterial molecules.

A team of scientists has just revealed an unsuspected function of the immune system, paving the way for new antibiotics. This discovery sheds light on a hidden ability of the proteasome, an essential ...