They assess recent human studies bolstering the notion that immunosuppression is also a major contributor to the disease. Many people with sepsis succumb to cardiac dysfunction, a process examined ...

CD47-amyloid-β-CD74 signaling is a key driver of adaptive immunosuppression in sepsis, suppressing B cells and impairing ...

In sepsis and atherosclerosis, DC ferroptosis contributes to immunosuppression. MDSCs, which suppress immune responses, have subtypes with varying ferroptosis resistance. Tumor-associated MDSCs ...

In sepsis, the inflammatory response spins so ... Timing is also critical, as immunosuppressive drugs need to be administered before any tissue damage has taken place. Instead, an ideal treatment ...

Pediatric critical care remains a pivotal frontier in modern medicine, confronting unique challenges shaped by the dynamic physiology and developmental ...

Sepsis is one of the deadliest conditions in intensive care units (ICUs), triggered by the body's out-of-control response to infection. Despite medical advancements, its in-hospital mortality rate ...

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression. Ferroptosis, driven by ...