Not all patients respond well to chimeric antigen receptor (CAR) T cell therapies, which reprogram a patient’s own immune cells to recognize and attack cancer. A way to optimize these treatments is to ...

The immune system relies on complex interactions between cells to orchestrate effective responses against pathogens and tumours. Among these, T cells play a pivotal role through their ability to ...

Scientists at the University College London (UCL) have developed a novel therapy that helps treat patients with T cell acute ...

A cutting-edge therapy using base-edited immune cells is offering a major breakthrough for patients with one of the toughest ...

How do we “name” a cell and assign its identity? How do we know that we are all talking about the same cells? How do we agree on what it takes to confidently correlate previous with current research ...

Innovative and cutting-edge technology transforms functional live-cell analysis by enabling precise, flexible, and scalable end-to-end immuno-oncology, antibody, and cell therapy discovery.

STEM-engineered CAR T cells performed as well as or better against cancer cells than did FDA-approved CAR T cells and kept their cancer-fighting abilities for longer.

Acute myeloid leukemia (AML) cells under the microscope, in purple. There is a serious need for finding better ways to treat AML that comes back after initial treatment. Chimeric antigen receptor (CAR ...

The regulatory division of the immune system is vital for its overall function. Immune T cells originate in the bone marrow and then travel to the thymus—a kind of biological police academy. 2 Here, ...