Meryl Streep and Emily Blunt were the first cast members confirmed to reprise their roles for the sequel. In June 2025, 20th Century Studios at last confirmed that Anne Hathaway and Stanley Tucci will also return. The company shared a video on Instagram announcing that the sequel is now in production, tagging both Hathaway and Tucci.

Deadline has shared that Simone Ashley has joined the cast of The Devil Wears Prada 2, which will bring back legacy cast members Anne Hathaway as Andy Sachs, Meryl Streep as Miranda Priestly, Emily Blunt as Emily,

"Bridgerton" actress Simone Ashley has joined the cast of “The Devil Wears Prada 2,” the sequel to the hit 2006 film.