According to a case–control study published in Neurology, the expression of proinflammatory cytokines is elevated in the affected skin of patients with small-fiber neuropathy (SFN).

Different types of diabetic neuropathy affect different areas of the body and cause a variety of symptoms ... For this, they’ll use nylon fiber to check your limbs for any loss of sensation.

In this test, plantar sweat production causes a quantifiable ... score, the neuropathy symptom score, and quantitative sensory function tests that indicate small-fiber denervation.