Shown are MRI scans of a Huntington’s disease (HD) sufferer’s brain (left) and a normal brain (right). In the HD brain, many brain cells have died and fluid (black areas) has filled in those ...

New research shows that the adult brain can generate new neurons that integrate into key motor circuits. The findings ...

Brain Changes in Huntington's Disease Decades Before Diagnosis Will Guide Future Prevention Trials Jan. 17, 2025 — Subtle changes in the brain, detectable through advanced imaging, blood and ...

UCLA Health researchers say study findings uncover Huntington's disease mechanisms and pave new ways to develop treatments.

Medically reviewed by Nicholas R. Metrus, MD Huntington’s disease is a hereditary disorder that causes a progressive decline ...

HD is a rare, adult-onset, autosomal dominant, progressive neurodegenerative disease. George Huntington (Figure 1) was the first person to provide a comprehensive description of adult-onset HD in ...

Mouse studies demonstrated that newly generated neurons connect with brain networks responsible for motor control.

Germline CAG-repeat expansions mean that the children of individuals with Huntington’s disease would inherit CAG repeats that are longer than those in the previous generation, increasing the ...

New research shows that the adult brain can generate new neurons that integrate into key motor circuits, findings that may point to a new way to treat neurogenerative disorders.

Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by a mutation in the gene called huntingtin on chromosome 4. HD is inherited in an autosomal dominant fashion, so that each ...