Shown are MRI scans of a Huntington’s disease (HD) sufferer’s brain (left) and a normal brain (right). In the HD brain, many brain cells have died and fluid (black areas) has filled in those ...

The number of people who have the gene that causes Huntington's disease in Northern Scotland has been accurately counted for ...

Breakthrough Therapy designation based on clinical evidence from Phase I/II trials showing meaningful slowing of disease progression ~ ~ Additional regulatory update and guidanc ...

Brain Changes in Huntington's Disease Decades Before Diagnosis Will Guide Future Prevention Trials Jan. 17, 2025 — Subtle changes in the brain, detectable through advanced imaging, blood and ...

HD is a rare, adult-onset, autosomal dominant, progressive neurodegenerative disease. George Huntington (Figure 1) was the first person to provide a comprehensive description of adult-onset HD in ...

This type of medication can help manage the uncontrolled movements that can occur with Huntington’s disease. Huntington’s disease is a neurodegenerative disorder that causes a progressive ...

Mouse studies demonstrated that newly generated neurons connect with brain networks responsible for motor control.

Huntington's disease (HD) is a hereditary neurodegenerative disorder caused by a mutation in the gene called huntingtin on chromosome 4. HD is inherited in an autosomal dominant fashion, so that each ...