Several vaginal potassium hydroxide and wet preparations ... Clinically relevant positive reactions to clotrimazole cream and purified clotrimazole were noted at 48 hours (Figure 2) and 96 hours.

Advise patients to not have vaginal intercourse or use tampons or douches during treatment with ovules. Pregnancy. Nursing mothers: monitor infant or consider alternatives.

Vaginal cream Conjugated equine estrogens Premarin 0.625 mg CEE/g 0.5–2.0 g/day or insert 0.5 g vaginally twice weekly Vaginal cream Estradiol Estrace 0.1 mg estradiol/g 2–4 g/day for 1–2 ...