Esketamine monotherapy demonstrated beneficial antidepressant effects at multiple doses for patients with treatment-resistant depression, according to results of a phase 4 randomized trial published ...

Interest in the use of ketamine for the treatment of depression has risen in recent years. Two clinicians discussed the lessons they have learned in using ketamine and esketamine as adjunctive ...

Esketamine is a form of ketamine that's similar to the original but has some unique features. It's called the S-enantiomer of ketamine, and it's more specific in how it works in the body.

“Ketamine is a combination of esketamine and r-ketamine…for all practical purposes, there may be slight differences, but it’s the same molecule, just differently wrapped up. 99.9% of ...

Ketamine has a long and varied past as a pharmaceutical. It was developed in 1962, tested on subjects in 1964 and approved as an anesthetic in 1970 in the United States. Ketamine was used in the ...

On March 6, 2019, the FDA approved a new ketamine nasal spray, called Esketamine, for the treatment of depression. Many clinics in the U.S. already offer similar ketamine IV infusion treatments ...

Levine said he has treated more than 3,000 patients with ketamine at his Actify Neurotherapies clinics. But he said he expects to stock esketamine within months "happily coexisting" with the older ...

Ketamine and esketamine did not have different cognitive effects on individuals with treatment-resistant depression, according to study results published in Psychiatry Research.“Despite the ...

To assess the cognitive safety of ketamine and esketamine, the Brazilian researchers analyzed 14 studies that included more than 1,000 patients with treatment-resistant depression who received ...

Research dating back to the early 2000s has shown that ketamine and esketamine — which is derived from ketamine — are effective in cases of so-called treatment-resistant depression, and the ...