CD4+ T cells, or helper T cells, are one type of lymphocyte that helps coordinate the immune response against infection and disease. They interact and activate other cells in the immune system.

Immunologists at UNIGE have revealed a previously unknown anti-tumor role of CD4 T lymphocytes, marking a breakthrough that ...

For decades, CD4+ T-cells were seen to have a primarily supportive role in the immune response to cancer, priming CD8+ T cells that would take the more active role in attacking cancer cells. However ...

Researchers are working to launch a first-in-human clinical trial to test the approach in patients with cancer who develop ...

Scientists are on the hunt for a unique set of mutations, called “neoantigens,” that let the immune system distinguish tumor cells from normal cells. Their goal is to help the immune system react to ...

CD4+ T cells, or helper T cells, are one type of lymphocyte that helps coordinate the immune response against infection and disease. The cells are crucial in achieving a regulated effective immune ...

CD4 and CD8 cells are both types of white blood cells called T cell lymphocytes. ... kind of like the General in a battle. One of these is your CD4, or helper T cells.

The cell-mediated immunity operates mainly through two types of T cells: CD8+ “killer” T cells and CD4+ “helper” T cells. ... Helper T cells themselves must be activated to gain function.

The molecular markers CD4 and CD8—defining helper T cells and killer T cells, respectively—were once considered mutually exclusive. But "double positive" CD4+-CD8+ T cells have lately been ...

The research groups led by Wolfgang Kastenmüller and Georg Gasteiger employed innovative microscopy techniques to observe how specific immune cells, known as T-cells, are activated and ...

The results, published in Science, challenge long-standing assumptions about the process called T-cell priming. ... There, they receive IL-2 from CD4 helper T-cells.