Secreting CXCLs, ILs, TGF-β, CCL12, PGE2, CAFs promote pro-cancer macrophage conversion, inactivate NK cells, and hinder CD8+T cell aggregation ... via amyloid-β protein, creating a feedback ...

MURA-8518 is designed to be a half-life extended, binding protein-resistant IL-18 in order to overcome ... nemvaleukin ...

MURA-8518 is designed to be a half-life extended, binding protein-resistant IL-18 in order to overcome ... nemvaleukin treatment leads to preferential expansion of antitumor CD8+ T cells and natural ...

Each cycle can use an antibody for a different protein. The result is a set of images ... a tumor sample stained immunohistochemically for CD8+ T-cellls with a Hematoxylin counterstain.

Dual blocking SHP2 and FGFR2 can not only promote the targeted tumor-killing effects and overcome FGFR2 inhibitor resistance caused by feedback activation, but also activate T cell-mediated anti-tumor ...

In biology, the binding of cellular proteins to molecules called ligands produces myriad functions essential for life, ...

Some of the body's cells stay put for life, while others are free to roam. To move, these migratory cells rely on ...

AlphaFold solved a structural biology riddle: predicting protein structure. And yet, CASP, a global competition born to solve that problem, lives on.

Scroll through TikTok or Instagram and you’ll be inundated with protein-centric recipes. Maximizing protein is a huge trend right now on social media—and not just in the usual suspects ...

The three-dimensional shape of a protein can be used to resolve deep, ancient evolutionary relationships in the tree of life, ...