Hosted on MSN17d
Pancreatic cancer RNA vaccine shows durable T cell immunity
In the Phase I trial, "RNA neoantigen vaccines prime long-lived CD8 + T cells in pancreatic cancer ... T cell receptor (TCR) sequencing, and longitudinal blood and tissue analyses over a median ...
University of Bristol4y
Translational immunology
The CD8+ T cell activation involves two key interactions: The TCR/pMHCI interaction: determines antigen specificity. Promiscuity is a characteristic feature of this interaction and it is essential for ...