Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...

While Russian Defence Ministry says 150 prisoners were swapped in a New Year deal, Zelenskyy welcomes 189 Ukrainians home. In this photo released by the Russian Defence Ministry Press Service ...

MALE, Maldives — In late 2023, Mohamed Muizzu became a problem for India. In fiery speeches, the newly elected president of the Maldives pledged to expel Indian troops stationed in his island ...

Department of Joint Surgery, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200120, China ...

Department of Biological Science and Technology, Center for Intelligent Drug Systems and Smart Bio-devices (IDS 2 B), National Yang Ming Chiao Tung University, Hsinchu 300, Taiwan Department of ...

Vagally mediated atrioventricular (AV) block is defined as a paroxysmal AV block, localised within the AV node, associated with slowing of the sinus rate. All types of second-degree AV block, ...

The peptide binds to the IgG site of the receptor and blocks FcRn-mediated transport of IgG, resulting in an 80% reduction in serum levels of IgG in cynomolgus monkeys without reducing serum albumin ...