Atlanta Falcons quarterback Kirk Cousins' 19-yard pass locates wide receiver Deven Thompkins as WR approaches sideline.

San Francisco's 41-year drought in Cleveland is over after the 49ers routed the Browns 26-8 to improve to 9-4 this season.

Christian McCaffrey battles his former team in primetime as the 49ers face the Panthers in the Week 12 finale.

Watch the best plays from San Francisco 49ers running back Christian McCaffery's 142-yard game against the Carolina Panthers ...

It wasn’t a pretty first half, but the San Francisco 49ers bounced back to blow out the Cleveland Browns in Week 13.

In Los Angeles, there's nothing spookier than the regular season edition of the San Francisco 49ers. Behind NFL history from former trade target Christian McCaffrey, the Los Angeles Rams were ...

Head Coach Kyle Shanahan highlighted standout performances on both sides of the ball, and emphasized the growth and execution ...

San Francisco 49ers running back Christian McCaffrey explained the significance of Roger Craig and Frank Gore's impact on his ...

The San Francisco 49ers put on a magnificent outing vs. the Atlanta Falcons despite a rash of injuries on both sides of the ball. 49ers fans at Levi's Stadium were treated to a 20-10 victory that ...

The Minnesota Vikings pulled out a 22-17 win over the San Francisco 49ers in a primetime clash at U.S. Bank Stadium on Monday night. Here’s what you need to know: Read more here. Need tickets? Here ...

In the aftermath of McCaffrey's departure, the Panthers surprisingly did not falter in their run game. Under interim coach Steve Wilks, the team adopted a more straightforward rushing strategy, ...

Christian McCaffrey remains extremely productive for the San Francisco 49ers in his age-29 season, and in at least one way, ...