Clathrin-mediated endocytosis is the main mechanism for internalization of cell-surface molecules and surface-bound cargoes. Although the machineries that drive the formation of endocytic vesicle ...

Clathrin-mediated endocytosis is a modular process that involves core and accessory adaptor proteins that package cargoes into vesicles, ultimately leading to their uptake. It is essential for ...

During clathrin-mediated endocytosis, adaptor proteins bind to the cell membrane and to the protein clathrin, assisting in ...

In clathrin-mediated endocytosis, the cell membrane invaginates to take up metabolites, hormones, and proteins from the cell surface into intracellular vesicles.

Living cells and tissues show a high capacity to absorb various chemical compounds from the surrounding environment.

Granseth B et al. Clathrin mediated endocytosis: the physiological mechanism of vesicle retrieval at hippocampal synapses. J Physiol 15:681-6 (2007). Read more (PubMed: 17599959) ...

Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and conveyed ...

Clathrin coated pits (CCPs) are spherical, cage-like structures located on the plasma membrane that are responsible for receptor-mediated endocytosis. CCPs bud off the cell membrane with their ...

Claudin-11 plays a pivotal role in the clathrin-mediated endocytosis of influenza A virus. Science China Press. Journal Science China Life Sciences DOI 10.1007/s11427-024-2856-y. Keywords ...

Disruption of endocytosis through chemical inhibition of clathrin heavy chain function. Nature Chemical Biology , 2019; DOI: 10.1038/s41589-019-0262-1 Cite This Page : ...

Of the 40 modifiers, 12 had clear human homologs, three with roles in clathrin-mediated endocytosis. One of these is the yeast version of PICALM, one of the top late-onset AD risk genes. The other two ...

An artist's impression of Clathrin-Mediated Endocytosis (CME) occurring as periodic traveling waves on the membrane. Clathin coated vesicles (blue) bud off from wave peaks. Clathrin waves require ...