Epidermal growth factor receptor (EGFR) is a major driver of cancer dissemination and target for anti-cancer therapies but ...

Several targets almost fulfill this requisite: tenascin-C, podoplanin/aggrus, EGF receptor (EGFR), EGFRvIII, human transferrin receptor, human neural cell adhesion molecule, L1 cellular adhesion ...

And the relationship of HDCA mediating the Epiregulin (EREG)/Epidermal Growth Factor Receptor (EGFR) signaling pathway through FXR was explored. Eight pairs of primary CRC and paracancerous tissue ...

This study presents a valuable finding on a potential signaling pathway responsible for the direct effects of ... Scientific), 1 mM N-acetyl-L-cysteine (Sigma-Aldrich), 50 ng/mL EGF (PeproTech, Inc., ...

PlexinD1 drives prostate cancer growth and plasticity via semaphorin ligand-dependent transactivation of ErbB3 and cMet to trigger the ERK/AKT pathways and subsequently noncanonical Gli1-dictated ...

TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan, China Oncology Teaching and Research ...

Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Bandung 45363, Indonesia Laboratory of Translational Pharmaceutical Research, Faculty of Pharmacy, ...

Results: RAGE upon activation by its ligands enhances downstream signaling pathways, contributing to breast cancer cells migration, growth, angiogenesis, metastasis, and drug resistance. In addition, ...

Figure 3 presents the QUORUM diagram. From the 930 references retrieved, we included 13 case–control (821 416 patients) and 8 cohort studies (784 818 patients). Details of the studies are presented in ...