ACROBiosystems has developed a series of specialized proteases for the screening and validation of ADC linkers, focusing on ...

Heterogeneous Hippo pathway (YAP/TAZ) activation in lung adenocarcinoma drives tumor progression by enabling ferroptosis ...

EGFR is a receptor on the surface of cells which is expressed in many normal epithelial tissues, including skin. The EGFR signaling pathway is one of the key pathways that regulate growth ...

Background Chronic inflammation and elevated reactive oxygen species are key contributors to hepatocellular carcinoma (HCC) ...

PI3Kγ signaling controls trafficking of CD8 + T cells between lymphoid and non-lymphoid organs and drives hypertension in a murine model The activation and infiltration of immune cells to the ...

Advertising Feature: Application Note Published: April 2009 Visualizing signal transduction pathways by quantifying protein-protein interactions in native cells and tissue Simon Fredriksson Nature ...

The ras-signaling pathway is implicated for mutated Neu-induced activation of transcription factors Ets, Ap-1, and NF-κB in NIH 3T3 cells (14). EGF modulates the expression of many cell growth-related ...

Gene regulatory pathways plays a significant role in personalized medicine. Because pathways often branch or converge, graphs are better at describing them. In this work, we introduced Neo4j, a graph ...