Cancer Gene Therapy - Antitumor efficacy of oncolytic herpes simplex virus adsorbed onto antigen-specific lymphocytes Skip to main content Thank you for visiting nature.com.

“This license, secured from the world’s leading academic laboratory focused on HSV antigen discovery, provides us a key strategic advantage and further strengthens our position as a leader in ...

HSV-1 antibodies are typically associated with oral herpes, and HSV-2 antibodies are primarily associated with genital herpes. Antigen tests for herpes identify specific HSV antigens from a lesion ...

Tests: Virus can be cultured, or HSV antigen can be detected with direct immunofluorescence and ELISA. Antibodies peak 12-21 days after initial infection, ...

There is no preventive vaccine or cure, but Genocea Biosciences has a prophylactic HSV-2 vaccine moving into a first in-human clinical trial in third quarter 2012, Chip Clark, president and CEO ...

BALTIMORE — The investigational herpes simplex virus-2 vaccine GEN-003 was well-tolerated and reduced viral shedding and genital lesions up to 1 year after vaccination, according to data ...

HSV-2-specific antibody concentrations in tissue were dynamic, spiking at the time of active lesions, while antigen-specific antibodies in the serum remained stable over time. To explain this result, ...

New evidence indicates that herpes simplex virus 1 prevents glycolipid antigen presentation to natural killer T cells by downregulating CD1d expression. Nature Immunology - Viruses have evolved ...

Genital herpes infection is one of the most common STDs that has no cure. ... This antigen detection test is performed along with a viral culture or can be done in its place.

TCR-dependent activation depends on antigen specificity, while bystander activation depends on cytokines. In a recent study, Dr. Jennifer Lund, ... (gB), which generated HSV-specific CD8 T cells.

- Statistically significant result on expected Phase 3 primary endpoint with Phase 3 dose -- Positive results on multiple secondary clinical endpo ...

An asymptomatic genital herpes infection is identified by HSV shedding or serologic evidence of antibody to HSV-2 ... or HSV antigen can be detected with direct immunofluorescence and ELISA.