Medically reviewed by Casey Gallagher, MD Psoriasis of the hands and feet, known as palmoplantar psoriasis, is an inflammatory autoimmune disorder that causes scaly, itchy skin patches on the palms ...

Dyshidrotic eczema (DE) is a chronic skin condition that causes small blisters on the palms of the hands, soles of the feet, ...

During pregnancy, at least a half of all women experience red, sore-looking skin on the palms of their hands or the soles of their feet. Often, these itch too, albeit it usually only mildly.