Loyal has a trio of longevity drugs in the works, including two meant to specifically target larger breeds that typically ...

They work by reducing levels of insulin-like growth factor 1 (IGF-1), a hormone that fuels cell growth. Scientists believe that high levels of IGF-1 shorten the lifespan of large dogs, which can ...

The drug could keep your pet around for longer—but some vets and ethicists worry that we might be barking up the wrong tree.

The pill, referred to as LOY-002, aims to reduce aging in dogs by combating the metabolic changes that can arise with age, such as diabetes mellitus (insulin resistance).

More specifically, the pill reduces frailty by suppressing aging-driven increases in insulin, thus reducing the risk of disease, extending health and decreasing the rate of aging.

Dr. Geller says he's enrolled about 50 dogs and is accepting more to test the daily pill. "It helps with potentially preventing insulin resistance. It helps with managing fats in your body.

For now, I’ll focus on the science-backed habits that help extend lifespan for both humans and dogs: a healthy diet, regular exercise, sleep and companionship—which just so happen to be my dog’s ...

Don’t worry, they haven’t forgotten the smaller dogs. Clinical trials are now under way for LOY-2, a pill that aims to improve metabolic fitness for dogs of nearly all sizes, as well as LOY-3 ...

Clinical trials are now under way for LOY-2, a pill that aims to improve metabolic fitness for dogs of nearly all sizes, as well as LOY-3—a pill version of LOY-1.