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3D animation depicts a peyote cactus, Lophophora williamsii, and its key psychoactive component, the mescaline molecule. Woman talking to therapist in his office A male psychologist is talking to a ...
The discovery of the clinically relevant serotonergic system in our brains owes a lot to this mysterious and highly potent semi-synthetic molecule. However ... with purported medicinal value (eg. 2C-B ...
Mescaline is under clinical development by Mind Medicine MindMed and currently in Phase I for Unspecified Psychiatric Disorders. According to GlobalData, Phase I drugs for Unspecified Psychiatric ...
Psilocybin is a naturally occurring compound derived from fungi with mind-altering qualities similar to those of LSD and mescaline. Most study participants experience profound alterations in ...
Single-molecule biophysics is the study of the dynamics and interactions of individual biomolecules to understand how they carry out their functions in living cells. For example, monitoring the ...
Enabling protein degradation with small-molecule drugs has emerged as an innovative approach to the development of therapeutics against otherwise intractable targets. Two landmark studies that ...
In April 2024, the EMA held a virtual briefing where it announced plans to revisit the potential of psychedelic compounds DMT, LSD, mescaline, and psilocybin for mental health conditions.
Attempts to design small molecule therapies directed to this cytokine have not led to approved products yet. Here we report the discovery and development of a potent small molecule inhibitor of TNF ...