0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune responses. The research, titled "Protein Phosphatase 2A Promotes CD8+ T ...

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PP2A, protein phosphatase 2; PTEN, phosphatase and tensin homolog; PTP1B, protein tyrosine phosphatase 1B. Figure 2. Primary signaling pathways involved in contraction-induced glucose uptake. AMPK, 5′ ...

Despite the wealth of available information regarding the activation by Akt, there remains a paucity of information regarding the cellular mechanisms that lead to Akt inactivation. In general, the ...