The Indiana Fever star and Indianapolis Colts legend appear in a new ad for Ascension St. Vincent hospital in Indianapolis.

Indiana Fever star Caitlin Clark and Indianapolis Colts legend Peyton Manning appeared in a spot for Ascension St. Vincent. The Peyton Manning Children's Hospital is located at Ascension. In the commercial, the two are in an operating room conducting a surgical procedure.

Peyton Manning has been an Indianapolis legend for almost three decades. Caitlin Clark is now the biggest star in Naptown. Therefore, it's not surprising that a business, or in this case, a hospital,

Iowa women's basketball star and reigning WNBA Rookie of the Year for the Indiana fever, starred in a commercial with Peyton Manning

Caitlin Clark And Peyton Manning starred in a hilarious commercial for the Ascension St. Vincent hospital in downtown Indianapolis.

Indiana Fever star Caitlin Clark and Hall of Fame quarterback Peyton Manning have teamed up in a lighthearted and impactful commercial

Peyton Manning’s back with another funny commercial. Last year, the former NFL quarterback teamed up with Nestlé Toll House to create “cookie nachos,” combining two iconic gameday snacks for football fans. As part of his new endorsement deal, Manning has also filmed a new commercial for the brand.

Caitlin Clark and Peyton Manning have combined their star power for a new ad. On Wednesday, a new commercial featuring Clark and Manning attempting surgery began circulating on social media. It's a funny ad where Clark questions Manning's attempt to perform heart surgery while they discuss how good the surgeons at Ascension St.