Evidence suggests that in Parkinson’s disease, a breakdown in lysosomal function allows lipids to build up within cells. Variants of the GBA1 gene, the strongest genetic risk factor for sporadic PD, ...

Discover how a structural breakthrough in the chikungunya virus is opening new avenues for antiviral drug development and ...

In a breakthrough with promising real-world applications, a team of Rutgers biophysicists, bioengineers, and plant biologists ...

Pancreatic cancer remains one of the most deadly malignancies, with nearly 52,000 deaths expected this year.  With limited therapeutic advances made i | Cancer ...

New research reveals that neurons can switch their migration strategy depending on whether they move on flat surfaces or through tight, crowded spaces.

A landmark review in Nature Reviews Genetics dissects the rare and common genetic variants that shape human height. The paper ...

The researchers found that TMBIM-2 works in coordination with the plasma membrane calcium pump MCA-3 (a PMCA homolog) to regulate synaptic Ca²⁺ balance, sustaining persistent calcium signaling ...

It binds both transmembrane and soluble TREM2, triggering a rise in CSF sTREM2. Single and multi-dose studies of the small ...

More precise characterization of the behavior of membrane-bound targets across various tissues ... and refinements to the target shedding model. Further, nonlinear protein and plasma binding, and ...

High-speed atomic force m (HS-AFM) reveals nanoscale differences in small extracellular vesicles (sEVs), improving biomarker ...