In the three aforementioned studies of epidural delivery of naloxone in combination with an opioid (fentanyl or morphine), the frequency of pruritus was decreased, with no reversal of analgesia noted.

Published reports on placebo-controlled clinical trials and other studies investigating the use of pure opioid antagonists for the prevention and treatment of opioid-induced pruritus (OIP ...

Itching (pruritus) can be more than a small annoyance. It can cause significant discomfort and may even become a distraction. You may be wondering how to know when itching is serious and how you ...