Researchers have uncovered a surprising connection between a cancer-related signaling pathway and the blood-brain and blood-retina barriers.

A University of Minnesota Medical School-led research team has discovered that a cancer signaling pathway has previously ...

The bispecific antibody market is experiencing rapid growth, primarily driven by the increasing prevalence of complex chronic diseases, such as cance ...

Intracellular Signaling Pathways Activated by TNF Receptors TNF signaling through TNFR1 and TNFR2 can elicit a variety of cellular responses depending on many factors including the metabolic state ...

Genetic approaches to investigate the role of TNF signaling in the nigrostriatal pathway have involved use of mice deficient in TNF and TNFRs but have yielded conflicting results.

Signaling pathways play an important role in the cell's response to its environment. Signaling pathways are often represented as directed graphs, which are not adequate for modeling reactions such as ...

Introduction The toll‐like receptor (TLR) signaling pathway is the front‐line subsystem against invasive microorganisms for both innate and adaptive immunity (Iwasaki and Medzhitov, 2004).

Key signaling pathways driving physical barrier formation. The formation of physical barriers is primarily driven by three core signaling pathways: TGF-β/Smad, Hippo-YAP/TAZ, and PDGF/PDGFR: ...