If you’re in a calorie deficit – either from dieting or while taking a weight loss drug – these exercises help direct your body to burn more fat instead and hang on to muscle. There’s also a beneficial metabolic effect: muscle tissue burns more calories at rest than fat, which can support long-term weight management.

Federal officials are targeting the blockbuster drugs as part of their ongoing initiative to lower drug costs.

T he newest weight-loss drugs, Wegovy and Zepbound, are incredibly popular. But doctors are still learning about all of the ways they affect the body—both helpful and harmful—beyond reducing weight. In report published in Nature Medicine,

About 140,400 obese patients in Massachusetts were prescribed medications like Wegovy and Zepbound in 2024, a 255 percent increase from 2023, according to a Globe analysis of insurance claims data.

Frozen’s Josh Gad shared insight into his weight loss journey after losing 40 pounds with the help of medication.