The current investigation exhibited the anticancer effect of nimbolide against N-methyl-N-nitrosourea (MNU) induced gastric cancer (GC) rats via apoptosis and NF-κB signaling pathway. Male Swiss ...

State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, Nanjing 210009, China ...

Inhibitors of Apoptosis Proteins (IAPs) are a family of anti-apoptotic proteins that play a pivotal role in apoptosis in general but also as oncoproteins in cancer progression and, more importantly, ...

The prescription cascade that follows is so well-documented, it can be said to involve prescribers with few stated concerns for how the drugs themselves interact—the compounding consequences of ...

One of the most common types of brain cancer, glioma, emerges when harmful mutations take place in the ‘glial’ cells tasked with supporting neurons. When these genetically damaged cells are not fixed ...

Her expertise is in personal finance and investing, and real estate. A cascade tax—also called a cascading tax—is a repeating sales tax that is imposed on products at each successive stage in ...

We subsequently show that Yap1 contextually protects differentiating, but not self-renewing, ESC from hyperactivation of the apoptotic cascade. Mechanistically ... modulating the expression of single ...