And the relationship of HDCA mediating the Epiregulin (EREG)/Epidermal Growth Factor Receptor (EGFR) signaling pathway through FXR was explored. Eight pairs of primary CRC and paracancerous tissue ...

Both EGF-family ... in signal attenuation. It is useful to distinguish between general attenuation, which functions at the level of the ligand–receptor complex, and pathway-specific inactivation ...

Results: RAGE upon activation by its ligands enhances downstream signaling pathways, contributing to breast cancer cells migration, growth, angiogenesis, metastasis, and drug resistance. In addition, ...