An unbiased separation method reveals distinct subpopulations of insulin secretory vesicles that undergo dynamic remodeling upon glucose stimulation.

The ionospheric electron density is influenced by solar radiation and the Earth’s atmosphere, with the impact factors broadly categorized into temporal and spatial features. This letter proposes a ...

Figure 1 Correlation between Homeostatic Model Assessment for insulin resistance (HOMA-IR) and fasting insulin (FINS) at the follicle-stimulating hormone (FSH) (panel A, B) and femoral neck bone ...

The 3-D ionospheric electron density is an important parameter for characterizing the ionosphere. Synthetic aperture radar (SAR), an advanced Earth observation technology, has shown its potential for ...

A, The normal hepatic mitochondrial morphology in the Sprague–Dawley control male rat model at 12 weeks of age. B, Mitochondrial abnormality in morphology in the 12-week-old transgenic Ren2 male rat ...

The parable of the blind men and the elephant suggests that scientists who study the same complex problem from different perspectives should pool their insights. This article touches four perspectives ...

The insulin sensitivity SI quantifies the ability of insulin to increase the effect of glucose on its own disappearance in a steady state. From Bergman's Minimal Model, mathematical models of the G-I ...

Mutations causing proinsulin misfolding trigger unfolded protein response and lead to impaired proliferation and reduced mTORC1 signalling of developing beta-cells in a patient-derived induced ...

The Standard Model predicts that particles surrounding electrons do affect an electron's shape, but at such an infinitesimal scale as to be pretty much undetectable using existing technology.