References Polydefkis M et al. (2004) The time course of epidermal nerve fibre regeneration: studies in normal controls and in people with diabetes, with and without neuropathy. Brain 127: 1606–1615 ...

Single fiber action potentials (SFAPs) from peripheral nerves, such as recorded with cuff electrodes, can be modelled as the convolution of a source current and a weight function that describes the ...

Sometimes, additional investigation such as spinal cord MRI, skin biopsy with epidermal nerve fiber density evaluation or even dorsal root ganglia biopsy is needed to reach the correct diagnosis 6, 12 ...

Pathological structural changes within the diabetic PNS include morphological and functional changes within peripheral nerve axons, the dorsal root ganglion, and epidermal nerve fibers. [3, 4 ...

According to Uppsala University, researchers have successfully used 3D printing to produce lab-grown models that closely resemble human nerve tissue —potentially accelerating drug development for ...

Key Findings: Analysis identified four central mechanisms consistently shared by CRPS and CD: 1) Small-fiber neuropathy defined by reductions in intraepidermal nerve fiber density and altered ...

Kelley, M.A. and Hackshaw, K.V. (2021) Intraepidermal Nerve Fiber Density as Measured by Skin Punch Biopsy as a Marker for Small Fiber Neuropathy Application in Patients with Fibromyalgia. Diagnostics ...

Electrical stimulation is usually applied percutaneously for facilitating peripheral nerve regeneration. However, few studies have conducted long-term monitoring of the condition of nerve regeneration ...

The dried fiber was milled in a Thomas Wiley grinding machine and screened to obtain fiber dimension of about 2 mm in size, making it ready for mixing with the polyethylene pellets. The dried fibers ...