“This causes a metabolic phenotype that resembles a glutamine synthetase deficiency, which can be characterized by increased ...

The nitrogen metabolism pathway overlaps with the biosynthesis of arginine and proline, with glutamate as the shared precursor. Histidine biosynthesis branches off the pentose phosphate metabolism.

The amino acid glutamine plays an unexpected role in erythropoiesis, the differentiation of erythroid progenitor cells into ...

Later we comment on the metabolic pathways in which the three classes ... In the liver, the oxidative deamination of glutamate results in α-keto-glutarate (a TCA cycle intermediate) and ammonia ...

The glutamate controls this process ... arresting the one-carbon metabolic pathway in cancer cells. "The locations of the ...

Disulfiram inhibits the normal metabolism of alcohol ... Acamprosate modulates glutamate neurotransmitter pathways through an unknown mechanism to reduce alcohol withdrawal hyperexcitability.