Most studies of the incidence of CCB-induced edema are based on subjective parameters (e.g., a collection of spontaneously reported adverse effects) and have been derived from clinical experience.

Pedal edema is caused mainly due to retention of fluid leaked from the damaged tiny blood vessels or capillaries. The commonly observed symptom is swelling. Diagnosis involves review of medical ...

The exact relationship of CCB therapy and edema is unknown. Since CCBs are potent arteriolar vasodilators and lack effects on venous capacitance vessels, it has been hypothesized by some that they ...